Clinical Investigator Collaborative

Legacy Project

Research Leaders:

14-OByrne Nair aellis
Dr. Paul O’Byrne, Professor, Div. of Respirology, Dept. of Medicine & Dean and Vice-President, Faculty of Health Sciences, McMaster University

Allergic Asthma CIC

Dr. Parameswaran Nair, Frederick E. Hargreave Teva Innovation Chair in Airway Diseases & Professor, Div. of Respirology, Dept. of Medicine, McMaster University

Severe Asthma CIC

Dr. Anne Ellis, James H. Day Chair of Allergic Diseases and Allergy Research; Associate Professor & Chair, Div. of Allergy & Immunology, Dept. Of Medicine, Queen’s University

Allergic Rhinitis CIC

Strategic Focus:

This multi-centre, Canadian-based Phase II clinical trials group fast-tracks early-stage potential drug candidates for allergic asthma, severe asthma and allergic rhinitis to accelerate the development of new therapies for allergic disease.

CIC Backgrounder
CIC Publications
Recent high-profile publications:

Projects:

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CIC Quality Assurance Plan

2008 - 2012

O’Byrne, Paul

CIC Quality Assurance Plan Statistical Analyses

2010 - 2012

O’Byrne, Paul

Development of a Microarray Genotyping Chip for Clinical Trials

2007 - 2009

Abugharbieh, Rafeed; Gauvreau, Gail; Hudson, Thomas; O’Byrne, Paul; Sandford, Andrew; Tebbutt, Scott; Wilkinson, Mark; Zamar, Ruben

Functional genomic and proteomic changes in response to nasal allergen challenge and following peptide immunotherapy treatment of the same: A partnership with the Allergic-Rhinitis Clinical Investigator Collaborative (AR-CIC) and industry  (Success Stories profile)

2010 - 2012

Adamko, Darryl; Ellis, Anne; Hickey, Pascal; Larche, Mark; Neighbour, Helen; Tebbutt, Scott; Wilson-McManus, Janet

Proposed Severe Asthma Network

2007 - 2009

Vethanayagam, Dilini

The Clinical Investigator Collaborative (CIC)-Allergic Asthma (AA)

2012 - 2016

Adamko, Darryl; Boulet, Louis-Philippe; Chakir, Jamila; Cockcroft, Don; Dahlen, Barbro; FitzGerald, Mark; Gauvreau, Gail; Leigh, Richard; Mayers, Irvin; O’Byrne, Paul; Tebbutt, Scott

The Clinical Investigator Collaborative (CIC)-Allergic Rhinitis (AR)  (Success Stories profile)

2012 - 2016

Adamko, Darryl; Boulet, Louis-Philippe; Ellis, Anne; Keith, Paul; Larché, Mark; Neighbour, Helen; Tebbutt, Scott; Vliagoftis, Harissios; Waserman, Susan

The Clinical Investigator Collaborative (CIC)-Severe Asthma

2012 - 2016

Boulet, Louis-Philippe; Dorscheid, Del; FitzGerald, Mark; Leigh, Richard; Lemiére, Catherine; Martin, James; Nair, Parameswaran

Allergic Rhinitis Clinical Investigator Collaborative (AR-CIC): Development of a standardized nasal allergen challenge model for a multi-center research collaborative to investigate novel therapeutic agents for allergic rhinitis (Success Stories profile)

2010 - 2012

Boulet, Louis-Philippe; Ellis, Anne; Keith, Paul; Neighbour, Helen; Ratz, Jodan; Vliagoftis, Harissios; Waserman, Susan

Clinical Investigator Collaborative (CIC) (Success Stories profile)

2007 - 2012

Befus, Dean; Bhutani, Mohit; Boulet, Louis-Philippe; Carlsten, Chris; Chakir, Jamila; Cockcroft, Don; Cormier, Yvon; Cote, Johanne; Cowie, Robert; Dahlen, Barbro; Dahlen, Sven-Erik; Dourado, Carlos; Field, Stephen; FitzGerald, Mark; Furci, Patrizia; Gauvreau, Gail; Hodges, Michael; Larché, Mark; Laviolette, Michel; Leigh, Richard; Martin, Joel; Matthews, John; Mayers, Irvin; O’Byrne, Paul; Tebbutt, Scott; Tiberi, Jean-Jacques; Vethanayagam, Dilini