CHILD Publications

Refereed Journal Articles

The database below lists the refereed journal articles that have emerged from the Canadian Healthy Infant Longitudinal Development (CHILD) Study.

The database can be sorted and/or searched by different data fields. When searching by author, use last name only.


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Author(s)YearTitleJournal
Kang LJ, Kolevaa PT, Field CJ, Giesbrecht GF, Wine E, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Kozyrskyj AL, and CHILD Study Investigators 2018

Maternal depressive symptoms linked to reduced fecal Immunoglobulin A concentrations in infants

Brain, Behavior, and Immunity

Dharma C, Lefebvre DL, Tran MM, Lou WYW, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Sears MR, the CHILD Study investigators 2018

Patterns of allergic sensitization and atopic dermatitis from 1 to 3 years: effects on allergic diseases

Clinical & Experimental Allergy

Stiemsma LT, Turvey SE 2017

Asthma and the microbiome: defining the critical window in early life

Allergy, Asthma & Clinical Immunology

Stearns JC, Zulyniak MA, de Souza RJ, Campbell NC, Fontes M, Shaikh M, Sears MR, Becker MB, Mandhane PJ, Subbarao P, Turvey SE, Gupta M, Beyene J, Surette MG, Anand SS for the NutriGen Alliance 2017

Ethnic and diet-related differences in the healthy infant microbiome

Genome Research

Bridgman SL, Azad MB, Field CJ, Haqq AM, Becker AB, Mandhane PJ, Subbarao P, Turvey SE, Sears MR, Scott JA, Wishart DS, Kozyrskyj AL, CHILD Study Investigators. 2017

Fecal Short-Chain Fatty Acid Variations by Breastfeeding Status in Infants at 4 Months: Differences in Relative versus Absolute Concentrations

Frontiers in Nutrition

Azad M, Vehling L, Lu Z, Dai D, Subbarao P, Becker AB, Mandhane PJ, Turvey S, Lefebrve DL, Sears MR, CHILD Study Investigators. 2017

Breastfeeding, maternal asthma, and wheezing in the first year of life: a longitudinal birth cohort study

European Respiratory Journal

Tran MM, Lefebvre DL, Dai D, Dharma C, Subbarao P, Lou W, Azad MB, Becker AB, Mandhane PJ, Turvey SE, Sears MR, the CHILD Study Investigators 2017

Timing of food introduction and development of food sensitization in a prospective birth cohort

Pediatric Allergy and Immunology

Tun HM, Konya T, Takaro TK, Brook JR, Chari R, Field CJ, Guttman DS, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Kozyrskyj AL, CHILD Study Investigators 2017

Exposure to household furry pets influences the gut microbiota of infant at 3-4 months following various birth scenarios

Microbiome

Graham C, Chooniedass R, Stefura WP, Becker AB, Sears MR, Turvey SE, Mandhane PJ, Subbarao P, CHILD Study Investigators , HayGlass KT. 2017

In vivo immune signatures of healthy human pregnancy: Inherently inflammatory or anti-inflammatory?

PLoS ONE

Zulyniak M, de Souza R, Mateen S, Desai,D, Lefebvre D, Gupta M, Wilson J, Wahl G, Subbarao P, Becker A, Mandhane P, Turvey S, Beyene J, Atkinson S, Morrison K, McDonald S, Koon T, Sears M, Anand S. 2017

Does the impact of a plant-based diet during pregnancy on birth weight differ by ethnicity? A dietary pattern analysis from a prospective Canadian birth cohort alliance

BMJ Open

Yasmin F, Tun HM, Konya TB, Guttman DS, Chari CJ, Becker A, Mandhane PJ, Turvey SE, Subbarao P, Sears MR, Scott JA, Dinu I, Kozyrskyj A 2017

Cesarean section, formula feeding and infant antibiotic exposure: separate and combined impacts on gut microbial changes in later infancy

Frontiers in Pediatrics, Neonatology

Tamana S, Smithson L, Lau A, Mariasine J, Young R, Chikuma J, Lefebvre DL, Subbarao P, Becker AB, Turvey SE, Sears MR, CHILD Study investigators, Pei J, Mandhane PJ 2017

Parent-Reported Symptoms of Sleep-Disordered Breathing Are Associated With Increased Behavioral Problems at 2 Years of Age: The Canadian Healthy Infant Longitudinal Development Birth Cohort Study

SLEEP

Chan D, Goruk S, Becker A, Subbarao P, Mandhane P, Turvey S, Lefebvre D, Sears M, CHILD Study investigators, Field C, Azad M 2017

Adiponectin, leptin and insulin in breastmilk: associations with maternal characteristics and infant body composition in the first year of life

International Journal of Obesity

Tran MM, Lefebvre DL, Dharma C, Dai D, Lou WYW, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Sears MR, and the CHILD Study investigators 2017

Predicting the atopic march: results from the Canadian Healthy Infant Longitudinal Development Study

Journal of Allergy and Clinical Immunology

Kovela P, Tun H, Konya T, Guttman D, Becker A, Mandhane PJ, Turvey S, Sears M, Subbarao P, Scott J, Kozyrskyj A 2017

Sex-specific impact of asthma during pregnancy on infant gut microbiota

European Respiratory Journal

Klopp A, Vehling L, Becker AB, Subbarao P, Mandhane PJ, Turvey SE, Lefebvre DL, Sears MR, the CHILD Study investigators, Azad MB 2017

Modes of infant feeding and the risk of childhood asthma: a prospective birth cohort study

Journal of Pediatrics

Arrieta MC, Arevalo A, Stiemsma LT, Dimitriu PA, Chico ME, Loor S, Vaca M, Boutin RCT, Morien E, Mingliang J, Turvey SE, Walter J, Wegener Parfrey L, Cooper P, Finlay BB 2017

Associations between infant fungal and bacterial dysbiosis and childhood atopic wheeze in a nonindustrialized setting

Journal of Allergy and Clinical Immunology

Arrieta MC, Sadarangani M, Brown EM, Russell SL, Nimmo M, Dean J, Turvey SE, Chan ES, Finlay BB 2016

A humanized microbiota mouse model of ovalbumin-induced lung inflammation

Gut Microbes

Arrieta MC, Walter J, Finlay BB 2016

Human Microbiota-Associated Mice: A Model with Challenges

Cell Host & Microbe

Yurist-Dousch S, Arrieta MC, Tupin A, Valdez Y, Antunes LC, Yen R, Finlay BB 2016

Nutrient Deprivation Affects Salmonella Invasion and Its Interaction with the Gastrointestinal Microbiota

PLoS ONE

de Souza RJ, Zulyniak MA, Desai D, Shaikh MR, Campbell NC, Lefebvre DL, Gupta M, Wilson J, Wahi G, Atkinson SA, Teo KK, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Sears MR, Anand SS for the NutriGen Alliance Investigators 2016

Harmonization of Food-Frequency Questionnaires and Dietary Pattern Analysis in 4 Ethnically Diverse Birth Cohorts

The Journal of Nutrition

Bridgman SL, Konya T, Azad MB, Sears MR, Becker AB, Turvey SE, Mandhane PJ, Subbarao P, CHILD Study investigators, Scott JA, Field CJ, Kozyrskyj AL 2016

Infant gut immunity: a preliminary study of IgA associations with breastfeeding

Journal of Developmental Origins Health and Disease

Subbarao P, Lu Z, Kowalik K, Brown M, Balkovec S, Gustafsson P, Lou W, Ratjen F 2016

Changes in multiple breath washout measures after raised volume rapid thoracoabdominal compression maneuvers in infants

Pediatric Pulmonology

Kozyrskyj AL, Kalu R, Koleva, PT, Bridgman SL 2016

Fetal programming of overweight through the microbiome: boys are disproportionately affected

Journal Developmental Origins Health and Disease

Sarah L. Bridgman, Konya T, Azad MB, Guttman DS, Sears MS, Becker AB, Turvey SE, Mandhane PJ, Subbarao P, CHILD Study Investigators, Scott JA, Field CJ, Kozyrskyj AL. 2016

High fecal IgA is associated with reduced Clostridium difficile colonization in infants

Microbes and Infection

Stiemsma L, Arrieta MC, Dimitriu P, Cheng J, Thorson L, Lefebvre D, Azad MB, Subbarao P, Mandhane P, Becker A, Sears M, Kollmann T, Mohn W, Finlay B, Turvey S. 2016

Shifts in Lachnospira and Clostridium sp. In the 3-month stool microbiome are associated with preschool-age asthma

Clinical Science

Pakpour S, Scott JA, Turvey SE, Brook JR, Takaro TK, Sears MR, Klironomos J 2016

Presence of Archaea in the indoor environment and their relationship with housing characteristics

Microbial Ecology

Bolduc FV, Lau A, Rosenfelt CS, Langer S, Wang N, Smithson L, Lefebvre D, Alexander RT, Dickson CT, Li L, Becker AB, Subbarao P, Turvey SE, Pei J, Sears MR, Mandhane PJ 2016

Cognitive enhancement in infants associated with maternal fruit intake during pregnancy: results from a birth cohort study with validation in an animal model

EBio Medicine

Azad MB, Sharma AK, de Souza R, Dolinsky VW, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Lefebvre DL, Sears MR and the CHILD Study investigators 2016

Association Between Artificially Sweetened Beverage Consumption During Pregnancy and Infant Body Mass Index

JAMA Pediatrics

Subbarao P, Sears M and the CHILD Study investigators 2015

The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma

Thorax

Arrieta M-C, Stiemsma LT, Dimitrui PA, Thorson L, Russell S, Yurist-Doutsch S, Mandhane P, Becker A, McNagny KM, Sears MR, Kollmann T, CHILD Study Investigators, Mohn WW, Turvey SE, Finlay BB. 2015

Early infancy microbial and metabolic alterations in children impact risk of asthma

Science Translational Medicine

Azad MB, Konya T, Guttman DS, Charie RS, Field CJ, Sears MR, Mandhane PJ, Turvey SE, Subbarao P, Becker AB, Scott JA, Kozyrskyj AL, CHILD Study Investigators. 2015

Impact of maternal intrapartum antibiotics, method of birth and breastfeeding on gut microbiota during the first year of life: a prospective cohort study

BJOG: An International Journal of Obstetrics and Gynaecology

Moraes T, Lefebvre DL, Chooniedass R, Becker AB, Brook JR, Denburg J, HayGlass KT, Hegele RG, Kollmann TR, Macri J, Mandhane PJ, Scott JA, Subbarao P, Takaro TK, Turvey SE, Duncan JD, Sears MR, Befus AD, the CHILD Study Investigators. 2015

The Canadian Healthy Infant Longitudinal Development (CHILD) Study: biological samples and biobanking

Paediatric and Perinatal Epidemiology

Azad MB, Konya T, Guttman DS, Field CJ, Sears MR, Hayglass KT, Mandhane PJ, Turvey SE, Subbarao P, Becker AB, Scott JA, Kozyrskyj AL and the CHILD study investigators 2015

Infant gut microbiota and food sensitization: associations in the first year of life

Clinical & Experimental Allergy

Takaro TK, Scott JA, Allen RW, Anand SS, Becker AB, Befus AD, Brauer M, Duncan J, Lefebvre DL, Lou W, Mandhane PJ, McLean KE, Miller G, Sbihi H, Shu H, Subbarao P, Turvey SE, Wheeler AJ, Zeng L, Sears MR, Brook JR and the CHILD study investigators 2015

The Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort study: assessment of environmental exposures

Journal of Exposure Science and Environmental Epidemiology

Sbihi H, Allen R, Becker A, Brook J, Mandhane P, Scott J, Sears M, Subbarao P, Takaro T, Turvey S, Brauer M 2015

Perinatal Exposure to Traffic-Related Air Pollution and Atopy at 1 Year of Age in a Multi-Center Canadian Birth Cohort Study

Environmental Health Perspectives

Kozyrskyj AL 2015

Can we predict future allergies from our infant gut microbiota?

Expert Review of Respiratory Medicine

Koleva PT, Kim J-S, Scott JA, Kozyrskyj AL. 2015

Microbial programming of health and disease starts during fetal life

Birth Defects Research (Part C)

Caulfield T, Burningham S, Joly Y, Master Z, Shabani M, Borry P, Becker A, Burgess M, Calder K, Critchley C, Edwards K, Fullerton SM, Gottweis H, Hyde-Lay R, Illes J, Isasi R, Kato K, Kaye J, Knoppers B, Lynch J, McGuire A, Meslin E, Nicol D, et al. 2014

A review of the key issues associated with the commercialization of biobanks

Journal of Law and Bioscience

Persaud RR, Azad MB, Chari RS, Sears MR, Becker AB, Kozyrskyj AL, the CHILD Study Investigators. 2014

Perinatal antibiotic exposure of neonates in Canada and associated risk factors: a population-based study

The Journal of Maternal-Fetal & Neonatal Medicine

Marhera A, Kahlke P, Lau A, Zeng Y, Hoskins C, Corbett T, Hemmings D, Mandhane P. 2014

You are how you recruit: a cohort and randomized controlled trial of recruitment strategies

BMC Medical Research Methods

Sbihi H, Brook JR, Allen RW, Curran J, Dell S, Mandhane P, Scott J, Sears MR, Subbarao P, Takaro T, Turvey SE, Wheeler A, Brauer M. 2013

A new exposure metric for traffic-related air pollution? An analysis of determinants of Hopanes in settled indoor house dust

Environmental Health

Konya T, Koster B, Maughan H, Escobar M, Azad MB, Guttman D, Sears MR, Becker AB, Brook JR, Takaro TK, Kozyrskyj AL, Scott JA. 2013

Associations between bacterial communities of house dust and infant gut

Environmental Research

Azad MB, Konya T, Maughan H, Guttman DS, Field CJ, Chari RS, Sears MR, Becker AB, Scott JA, Kozyrskyj AL, CHILD Study Investigators. 2013

Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months

Canadian Medical Association Journal

Azad M, Konya T, Maughan H, Guttman DS, Field CJ, Chari RS, Sears MR, Becker A, Scott JA, Kozyrskyj AL. 2013

Infant gut microbiota and the hygiene hypothesis of allergic disease: impact of household pets and siblings on microbiota composition and diversity

Allergy, Asthma & Clinical Immunology

Azad MB, Becker AB, Guttman DS, Sears MR, Scott JA, Kozyrskyj AL, on behalf of the CHILD Study Investigators 2013

Gut microbiota diversity and atopic disease: does breastfeeding play a role?

Journal of Allergy and Clinical Immunology

Lum S, Stocks J, Stanojevic S, Wade A, Robinson P, Gustafsson P, Brown M, Aurora P, Subbarao P, Hoo A-F, Sonnappa S. 2012

Age and height dependence of lung clearance index and functional residual capacity

European Respiratory Journal

Arrandale VH, Brauer M, Brook JR, Brunekreef B, Gold DR, London SJ, Miller JD, Ozkaynak H, Ries NM, Sears MR, Silverman FS, Takaro TK 2011

Exposure assessment in cohort studies of childhood asthma

Environmental Health Perspectives

Master Z, Ries N, Caulfield T. 2011

Balancing Efficiency and the Protection of Research Participants: Canadian Allergy/Asthma Researchers’ Perspectives on the Ethics Review of Multi-Site Health Research

Journal of Clinical Research and Bioethics

Ries N, LeGrandeur J, Caulfield T. 2010

Handling ethical, legal and social issues in birth cohort studies involving genetic research: responses from studies in six countries

BMC Medical Ethics

Subbarao P, Becker A, Brook JR, Daley D, Mandhane PJ, Miller GE, Turvey SE, Sears MR on behalf of the CHILD Study Investigators. 2009

Epidemiology of asthma: risk factors for development

Expert Review of Clinical Immunology

Subbarao P, Mandhane PJ, Sears MR. 2009

Asthma: epidemiology, etiology and risk factors

Canadian Medical Association Journal

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