Resources for Researchers & Trainees

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RESEARCH TOOLS & PLATFORMS

Allergy and Asthma Portal (AAP)


AllerGen’s Allergy and Asthma Portal (AAP) is a unique, web-accessible database specifically geared to the study of allergy and asthma. The AAP is the first resource of its kind and represents the most comprehensive database of the genes, proteins, biomolecular interactions and pathways associated with immunity and allergic disease.


Developed by Dr. Fiona Brinkman, the AAP is built upon InnateDB, an AllerGen-enabled database that has assembled the network of all known molecular interactions in humans and mice. The AAP incorporates over 900 additional biomolecular interactions relevant to allergy and asthma curated from both the scientific literature and AllerGen research.


The AAP is available for use by allergy and asthma researchers worldwide. It will improve scientists’ understanding of molecular pathways and aid in the development of new therapies for allergies and asthma.


Press Release

CHILD Study Biological Samples


AllerGen’s Canadian Healthy Infant Longitudinal Development (CHILD) Study, led by Dr. Malcolm Sears, is a birth cohort study looks at how the environment that a child is exposed to from before birth until age five can interact with genetics to cause allergies, asthma and other chronic diseases. The CHILD Study recruited 3,600 pregnant Canadian mothers and has is carefully assessing each child and its respective environment by collecting detailed housing, dietary and socio-economic information, dust from homes, and biological samples such as breast milk, blood from parents and children, and children’s urine, feces and nasal secretions.


As of March 31, 2014, almost 13,000 biological samples had been released by the CHILD Study for analysis. By 2017, this research platform will have collected more than 500,000 questionnaires and over 600,000 biological samples that will be available to scientists investigating the early-life origins and development of asthma, allergies, and other chronic immune/inflammatory diseases.


To inquire about accessing CHILD Study samples or information, contact AllerGen or the CHILD Study.


Genapha Database


Genapha, developed by Dr. Denise Daley and her team of researchers from the University of British Columbia, is an interactive website database that supports the world’s largest candidate gene study of asthma and allergy.


Genapha: Harnessing the Power of the World Wide Web

Genapha—A global resource for allergy and asthma researchers

Hybrid Laboratory


The Hybrid Laboratory (HL) is a formal partnership between AllerGen and the Hamilton Regional Laboratory Medicine Program (HRLMP) to provide leading-edge laboratory allergy and immune testing. By combining the excellence and expertise found in Hamilton Hospitals, McMaster University and AllerGen, and capitalizing on the synergies engendered by long-term partnership, the HL facilitates completion of the projects and initiatives that would be difficult for any one institute to fully realize.


Read more

InnateDB


Led by Dr. Fiona Brinkman, InnateDB is an AllerGen-enabled, public database of the genes, proteins, molecular interactions and pathways involved in allergic responses in humans and mice. InnateDB provides a platform for sophisticated investigations of asthma and allergy responses and can be combined with bioinformatics and visualization tools for more holistic, systems-level analyses that were not previously possible.


McMaster Health Forum


Under the leadership of Dr. Anthony Levinson, the McMaster Health Forum strives to be a leading hub for improving health outcomes through collective problem solving. Operating at the regional, provincial and national levels, the Forum harnesses information, convenes stakeholders and prepares action-oriented leaders to meet pressing health issues creatively. AllerGen researchers can leverage the tools and services of the Forum to advance their AllerGen-supported research goals.


Platform for Outcomes Research & Translation in Asthma & Allergy


Led by Dr. Larry Lynd, the Platform for Outcomes Research & Translation in Asthma & Allergy (PORTAL) provides a mechanism for systematically evaluating outcomes including costs, cost-effectiveness, quality of life, burden of illness, and preferences for health care interventions and programs, and translating evidence related to the identification, management, and prevention of allergy-related diseases.


Surface PARTiculate mAtter Network (SPARTAN)


Surface PARTiculate mAtter Network (SPARTAN) is a global network that uses ground-level air pollution monitoring devices to measure levels of fine particulate matter (PM2.5). Involving the participation of Dr. Michael Brauer, SPARTAN measures hourly PM2.5, primarily in highly populated regions in close proximity to existing ground-based sun photometers. These measurements evaluate and enhance satellite-based estimates of ground-level particulate matter (PM2.5). SPARTAN data is publicly available.


Network-wide Research Platforms


The James Hogg Research Centre


Formerly the iCAPTURE Centre


Medium scale genotyping (TaqMan), mRNA gene expression analysis (ABI), Biomarker measurement (Luminex), Cell analyisis (immunohistochemistry) and Flow Cytometry


Website

Manitoba Centre for Health Policy


Population-based health care databases

NANUC – University of Alberta


The National High Field NMR Centre

NMR spectroscopy and analysis


Occupational and Environmental Health Division


The Division of Occupational and Environmental Health in the Dalla Lana School of Public Health (DLSPH) has close linkages with the Department of Medicine at the University of Toronto, and the Department of Occupational Medicine at St. Michael’s Hospital. Its vision is to lead in public health research, education and service for a healthier Canada and a healthier world.


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COMMERCIALIZATION & KNOWLEDGE MOBILIZATION (KMb) RESOURCES

Knowledge Translation Planning Tools for Allergic Disease Researchers

Other Knowledge Translation (KT) Resources


The following non-AllerGen KT resources are offered as potentially useful to Network researchers. AllerGen is not responsible for the content of these resources, and does not review, contribute to, or endorse any information or products found therein unless specifically noted.


KT Planning Guide of Guides (York University and NeuroDevNet)


Knowledge Translation Tools and Resources (Vancouver Island Health Authority)


KT Clearinghouse (CIHR-funded)


Guide to KT Planning at CIHR: Integrated and End-of-Grant Approaches (CIHR)


KT Tools (NeuroDevNet)


Lab for KT in Health (Western University)


Registry of KT methods and tools for public health (National Collaborating Centre for Methods and Tools)

Commercialization Brochure



Commercializing your research: From Lab to Life guides Network investigators through the steps involved in assessing and developing the commercial potential of AllerGen-supported research results. This brochure outlines the initial steps in research commercialization—from discovery through disclosure and “pre-incubation” planning—as well as the types of support available from university technology transfer offices (TTOs) and the AllerGen Administrative Centre.

KTEE Mentorship Program


AllerGen’s KTEE (Knowledge and Technology Exchange and Exploitation) Mentorship Program provides Network investigators and their teams with advice and mentorship to aid in the planning and realization of knowledge translation initiatives and in the successful launch and growth of new ventures arising from AllerGen-sponsored projects.


Mentorship Program Fact Sheet

KTEE Webinars & Related Resources


PLANNING FOR RESEARCH SUCCESS (2015-16 WEBINAR SERIES)


Business Planning for Research Commercialization


with Jason Ding (TEC Edmonton)


Key Messages | Slide Presentation | Video

Assessing the Market Potential for a New Therapeutic


with Jonathon Jafari (CDRD)


Key Messages | Slide Presentation | Video

How to Attract Investment & Partners


with Dr. Brian Underdown (Lumira Capital)


Key Messages | Slide Presentation | Video

Experiences of a Scientific Entrepreneur


with Dr. Pieter Cullis (University of British Columbia)


Key Messages | Slide Presentation

Planning for Policy Impact: Lessons Learned


with Dr. Antoine Hakim (Stroke Network)


Key Messages | Slide Presentation | Video

Strategic Initiatives - Commercialization & KMb (single-year)


The SI program focuses on supporting just-in-time research and development opportunities that arise in-year and/or require a rapid response in order to generate, promote or accelerate the economic and social benefits of previous or new AllerGen research investments. These funds are intended to provide support for post-discovery commercialization, business planning and knowledge dissemination, mobilization, or translation activities.


The projects must be scaled so as to be achievable within a one-year/12 month timeframe and be aligned with AllerGen’s mission and vision.


SI Overview & Application Guidelines

Application templates:


SI Appendices  |  SI Project Narrative


Consultation Confirmation: Research Leader


Consultation Confirmation: Managing Director





























SI Submission Deadlines Dates for notification of results
March 27, 2017 May 18, 2017
September 25, 2017 November 16, 2017
January 29, 2018 March 15, 2018
March 26, 2018 May 17, 2018
September 12, 2018 October 29, 2018

Questions: please contact AllerGen Research Programs Manager April O’Connell at 905-525-9140 x26553 or apriloconnell@allergen-nce.ca


Multi-year Strategic Initiatives - Commercialization & KMb


The MSI program focuses on supporting larger-scale, longer-term, high-impact commercialization and/or knowledge mobilization initiatives aligned with AllerGen’s mission and vision and undertaken in partnership with AllerGen stakeholder/end-user organizations.


AllerGen will consider proposals for projects to be completed within a period of up to three years.


MSI Overview & Application Guidelines

Application templates:


To obtain MSI application templates, please contact AllerGen Research Programs Manager April O’Connell at 905-525-9140 x26553 or apriloconnell@allergen-nce.ca

MSI Appendices  |  MSI Project Narrative


Consultation Confirmation: Research Leader


Consultation Confirmation: Managing Director





























MSI Submission Deadlines Dates for notification of results
March 27, 2017 May 18, 2017
September 25, 2017 November 16, 2017
January 29, 2018 March 15, 2018
March 26, 2018 May 17, 2018
September 12, 2018 October 29, 2018

Questions: please contact AllerGen Research Programs Manager April O’Connell at 905-525-9140 x26553 or apriloconnell@allergen-nce.ca



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RESEARCH CAPACITY-BUILDING PROGRAMS

Travel Awards


AllerGen’s Travel Awards program supports AllerGen investigators’ and HQPs’ attendance at and participation in national and international conferences, symposia and workshops that are aligned with AllerGen`s mission, vision and goals.


Travel Awards

Research Skills Acquisition Awards


AllerGen’s Research Skills Acquisition Awards program supports AllerGen investigators’ and HQPs’ participation in workshops or other individual training opportunities, including lab exchanges, internships and equipment transfers, that facilitate the acquisition of specialized technical and laboratory skills relevant to AllerGen research.


Research Skills Acquisition Awards

Other Funding & Training Awards for HQP


AllerGen provides support for various capacity-building opportunities for HQP.


Other Funding & Training Awards for HQP

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ADMINISTRATIVE RESOURCES (Policies and Related Documents)

Travel Policy & Expense Claim


This policy outlines, for AllerGen participants and Institutional administrators, the acceptable use of AllerGen funds for travel (i.e., which expenses are eligible for reimbursement) and how to process a claim.


Travel Policy & Expense Claim Form

New Network Investigator Policy


This policy outlines the requirements for eligibility, and the process for becoming an AllerGen Network Investigator.


New Network Investigator Policy

AllerGen Attribution Statements


This document provides a selection of recommended citations to facilitate acknowledgment of AllerGen support.


AllerGen Attribution Statements

AllerGen Code of Conduct


This Code of Conduct outlines expectations for participant behavior at AllerGen-sponsored events, the process for handling complaints, and the repercussions of unacceptable behaviour.


AllerGen Code of Conduct

AllerGen Way of Working


This document outlines the norms promoted by AllerGen to define its members’ way of working together.


AllerGen Way of Working - Values Statement

NCE Agreement document


The NCE Standard Network Agreement outlines the terms and conditions by which the Network will fund certain research activities carried out at Participating Institutions by Network Investigators,, setting out the obligations of the parties and providing for such matters as reporting requirements, use of research funds, and ownership and exploitation of intellectual property.


NCE Agreement document