Category: Publications/Research updates

Infants who sleep less may have lower cognitive and language skills by age two

Does your child sleep less than 12 hours over a 24-hour period? Does he or she breathe through the mouth, snore or have pauses in breathing while asleep? New CHILD Study research has examined the impact of an infant’s sleep

Chris Carlsten advocates for the study of complex, real-world exposures in CHEST

Imagine if your allergy or asthma management plan took into account not only the nature of your allergic condition, but also the level of traffic pollution in your neighbourhood, the proximity of your house to an allergen-intensive green space, and

Breastmilk sugars known as HMOs may help prevent food allergies

Findings from AllerGen’s CHILD Study indicate that complex sugars in breastmilk, known as human milk oligosaccharides (HMOs), may reduce the risk of babies later developing food allergies. “Our research has identified a ‘beneficial’ HMO profile that was associated with a

Review paper from Jordana-Waserman lab tackles Th2 sensitivity

Foods that are harmless to most people may trigger anaphylaxis—a sudden, life-threatening reaction—in sensitized (or allergic) individuals. DrS Manel Jordana and Susan Waserman, AllerGen investigators and professors at McMaster University, are trying to find out what causes the body’s immune

Building a better nasal allergen challenge: new AR-CIC publication

AllerGen investigator Dr. Anne Ellis (Queen’s University) and her team have produced a clinically validated protocol for conducting nasal allergen challenges (NACs) in clinical trials. The optimized protocol, and its application in a unique cat allergy study, is described in

Infant feeding method influences baby’s gut bacteria, risk of overweight

New findings from AllerGen’s CHILD Study indicate that exclusive breastfeeding in early infancy protects babies from becoming overweight by age one. The study involved 1,087 Canadian mothers and infants participating in the CHILD Study and found a 63% increased risk

New ResearchSKETCH: New blood test predicts ‘late-phase’ asthmatic response

Recent AllerGen research has identified blood molecules that may help scientists better understand the biology of allergic asthma. AllerGen HQP Dr. Amrit Singh wants you to know more about this discovery, which emerged from research he participated in with AllerGen

New ResearchSKETCH: Can mom’s distress increase baby’s allergy risk?

Recent AllerGen research leveraging CHILD Study data sheds light on the link between a mom’s psychological wellbeing and the immune health of her newborn. AllerGen HQP Liane Kang wants you to know more about this discovery, which emerged from research

Exclusive breastfeeding in hospital associated with longer breastfeeding duration

New findings from AllerGen’s CHILD Study show that exclusive breastfeeding during the first few days of life is positively associated with longer-term breastfeeding, while in-hospital formula use is associated with breastfeeding for a significantly shorter duration. Dr. Meghan Azad led

C-sections and gut bacteria increase risk of childhood obesity

New CHILD Study research has found that overweight and obese women are more likely to have children who are overweight or obese by three years of age—and that bacteria in the gut may be partially to blame. “We know that

“Direct breastfeeding seems most protective against asthma development”

An article in MD Magazine will help physicians use CHILD Study research on breastfeeding to provide better patient care. The article highlights the finding, published in Journal of Pediatrics in November 2017, that direct breastfeeding in the first three months

Drug allergies mistreated and undiagnosed: new study

A new Canadian study sheds light on drug-induced anaphylaxis—an unpredictable and potentially fatal allergic reaction to medications, about which surprisingly little is known. The findings, published in the open-access journal Immunity, Inflammation and Disease, reveal that drug-induced anaphylaxis (DIA) represents

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