Category: Publications/Research updates

Molecular “fingerprinting” finds altered levels of sensor proteins in asthmatics

AllerGen researchers at McMaster University have found that people with mild allergic asthma have altered levels of “sensor” proteins that defend against infection and disease. Toll-like like receptors (TLRs) are proteins that play a key role in detecting and responding

Posted in Publications/Research updates

Why are some food allergies lifelong?

New research by AllerGen investigators Drs Manel Jordana and Susan Waserman and their team at McMaster University helps to explain why allergies to some foods, such as peanut, may persist for a lifetime. The study, published in the Journal of

Posted in Publications/Research updates

Diabetes in pregnancy associated with impaired lung function and childhood asthma

Diabetes in pregnancy may lead to impaired lung development and poor respiratory health among infants, according to a new review paper by researchers at the Developmental Origins of Chronic Diseases in Children Network (DEVOTION) in Manitoba. The article, “Diabetes in

Posted in Publications/Research updates

National study examines relationship between immigration status and the prevalence of non-food allergies

A study published in the Canadian Journal of Public Health has found that immigrants to Canada have fewer non-food allergies than the non-immigrant population, but that the difference diminishes with longer duration of residence in Canada. The study, which is

Posted in HQP / Trainee News, Publications/Research updates

Canadian alternative medicine clinics: over half make unproven allergy/asthma claims

The majority of Canadian chiropractic, naturopathic, homeopathic and acupuncture clinics claim that they can diagnose or treat allergy/sensitivity and asthma, according to an AllerGen study of nearly 400 clinic websites. The research, published December 17, 2016, in BMJ Open, analyzed

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CIC researchers find new drug more effective than Xolair

A new study by researchers in AllerGen’s Clinical Investigator Collaborative (CIC) has shown that a developmental drug, QGE031 (ligelizumab), is three times more effective than Xolair (omalizumab) in reducing symptoms of mild allergic asthma. The research, led by Dr. Gail

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Immunotherapy technique holds promise for curing food allergies

AllerGen Research Leader Dr. John Gordon and his team at the University of Saskatchewan have developed a new immunotherapy technique that reverses food allergies in mice. Their research was co-funded by AllerGen and CIHR. The findings, published in the Journal

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Anaphylaxis recurrence in kids: New C-CARE findings

A new study by AllerGen researchers suggests that nearly 18% of children who are treated medically for an anaphylactic reaction will experience another episode of anaphylaxis within a year. The study also found that children with food-induced anaphylaxis and children

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AllerGen researchers find possible key to fibrosis in mouse model of Crohn’s disease

New research by AllerGen investigators at The University of British Columbia (UBC) has found that a group of immune cells known as Group 3 innate lymphoid cells (ILC3) could be the key to the development of fibrosis in a mouse

Posted in Investigator news, Publications/Research updates

Does thumb sucking ward off allergies?

Children who suck their thumbs or bite their nails may have a lower risk of developing allergies, according to new findings published in the journal Pediatrics. “While we don’t recommend that these habits be encouraged, there does appear to be

Posted in CHILD Study, Investigator news, Media coverage, Publications/Research updates

Bullying of children with food allergy: its influence on wearing medical identification

Does bullying play a role in a child’s decision whether or not to wear medical identification jewelry for a food allergy? New Canadian research suggests that it does. A study of 110 children and teens with food allergy found that

Posted in Investigator news, Publications/Research updates

CHILD Study shows link between IgA and C. difficile bacteria

A new study from AllerGen’s Canadian Healthy Infant Longitudinal Development (CHILD) Study is the first to show an association between early gut immune development and colonization with Clostridium difficile (C. difficile)—a bacteria known to be a risk factor for future

Posted in CHILD Study, Investigator news, Publications/Research updates