Category: Publications/Research updates

Phase III trial shows new drug can help patients with severe asthma reduce oral steroids

An international study has shown that a new injectable drug (benralizumab) successfully targets the receptor of the immune system protein interleukin-5 (IL-5), allowing patients with hard-to-control asthma associated with blood or sputum eosinophils to reduce or discontinue oral steroids while

Posted in Investigator news, Publications/Research updates

A child’s unique “web of exposures” can affect lung health

Naturally, aspects of a person’s environment are connected, but until recently, scientists lacked the tools to visualize this complex web. The “exposome” concept maps environmental exposures and shows how they can affect a person’s health. In the first study to

Posted in Publications/Research updates

Can breastfeeding help protect babies from wheezing?

New research published 2 May 2017 in the European Respiratory Journal by AllerGen trainee Lorena Vehling and AllerGen investigator Dr. Meghan Azad shows that breastfed babies have a reduced rate of wheezing, putting them at a lower risk for asthma

Posted in CHILD Study, Publications/Research updates

Virtual breastfeeding communities: a project inspired at AllerGen event

What do Instagram, breastfeeding, a Manitoba-based epidemiologist and an Alberta-based digital technology expert have in common? They all come together in a new research project, with the AllerGen network as the catalyst. At AllerGen’s 2016 Research Conference in Vancouver, BC,

Posted in Investigator news, Publications/Research updates

Pet exposure during early life affects infant gut microbiota

Owning a cat or dog might be a good thing when it comes to reducing the risk of childhood allergies and obesity, according to new findings from the Canadian Healthy Infant Longitudinal Development (CHILD) Study. The research, published in the

Posted in CHILD Study, Investigator news, Publications/Research updates

Molecular “fingerprinting” finds altered levels of sensor proteins in asthmatics

AllerGen researchers at McMaster University have found that people with mild allergic asthma have altered levels of “sensor” proteins that defend against infection and disease. Toll-like like receptors (TLRs) are proteins that play a key role in detecting and responding

Posted in Publications/Research updates

Why are some food allergies lifelong?

New research by AllerGen investigators Drs Manel Jordana and Susan Waserman and their team at McMaster University helps to explain why allergies to some foods, such as peanut, may persist for a lifetime. The study, published in the Journal of

Posted in Publications/Research updates

Diabetes in pregnancy associated with impaired lung function and childhood asthma

Diabetes in pregnancy may lead to impaired lung development and poor respiratory health among infants, according to a new review paper by researchers at the Developmental Origins of Chronic Diseases in Children Network (DEVOTION) in Manitoba. The article, “Diabetes in

Posted in Publications/Research updates

National study examines relationship between immigration status and the prevalence of non-food allergies

A study published in the Canadian Journal of Public Health has found that immigrants to Canada have fewer non-food allergies than the non-immigrant population, but that the difference diminishes with longer duration of residence in Canada. The study, which is

Posted in HQP / Trainee News, Publications/Research updates

Canadian alternative medicine clinics: over half make unproven allergy/asthma claims

The majority of Canadian chiropractic, naturopathic, homeopathic and acupuncture clinics claim that they can diagnose or treat allergy/sensitivity and asthma, according to an AllerGen study of nearly 400 clinic websites. The research, published December 17, 2016, in BMJ Open, analyzed

Posted in Publications/Research updates

CIC researchers find new drug more effective than Xolair

A new study by researchers in AllerGen’s Clinical Investigator Collaborative (CIC) has shown that a developmental drug, QGE031 (ligelizumab), is three times more effective than Xolair (omalizumab) in reducing symptoms of mild allergic asthma. The research, led by Dr. Gail

Posted in Publications/Research updates

Immunotherapy technique holds promise for curing food allergies

AllerGen Research Leader Dr. John Gordon and his team at the University of Saskatchewan have developed a new immunotherapy technique that reverses food allergies in mice. Their research was co-funded by AllerGen and CIHR. The findings, published in the Journal

Posted in Publications/Research updates