Category: Publications/Research updates

Study finds asthma & food allergies predictable at age 1

A press release issued by The Journal of Allergy and Clinical Immunology (JACI) highlights new findings from AllerGen’s CHILD Study that will help doctors better predict which children will develop asthma and allergies. Analyzing data from more than 2,300 children

Stress in pregnancy may affect a baby’s immune system

Infants born to mothers experiencing distress may be at a higher risk of developing allergic disease, according to new findings published online in Brain, Behavior and Immunity. The study analyzed data from 403 infants and their mothers participating in AllerGen’s

Asthma risk lower with direct breastfeeding: CHILD Study

Direct breastfeeding in the first three months of life appears to provide more protection against childhood asthma than either infant formula or expressed breastmilk, according to new findings from AllerGen’s CHILD Study. The researchers analyzed data from 2,534 infants who

New genetic clue to peanut allergy

AllerGen researchers have pinpointed a new gene associated with peanut allergy. The gene, c11orf30/EMSY, is already known to play a role in other allergy-related conditions, such as eczema, asthma, and allergic rhinitis. This study is the first to associate the

CIC-tested biologic poised to become a “game-changing, blockbuster” asthma drug

In 2014, AllerGen’s Clinical Investigator Collaborative (CIC) conducted an early Phase II clinical trial on the injectable biologic drug tezepelumab, developed by MedImmune (the biologics arm of AstraZeneca) and Amgen, and first identified the drug’s significant therapeutic potential. “Now, it’s

Breastmilk hormones may help prevent obesity in infants

For years, scientists have attempted to understand the complexities of human milk—what it’s made of, how it’s produced, and how its unique composition affects an infant’s growth and development. In a new study published in the International Journal of Obesity,

Protecting against peanut allergy in children: new findings

Eating peanut while breastfeeding and early peanut introduction may help protect against peanut allergy in children, according to a new study led by researchers at the Children’s Hospital Research Institute of Manitoba and the University of Manitoba and published in

AllerGen researchers find potential biomarker for occupational asthma

AllerGen investigators Drs Chris Carlsten and Scott Tebbutt may have found a blood biomarker that can be used to diagnose an occupational asthma associated with the BC forestry industry. For a decade, Dr. Carlsten and his team have been diagnosing

AllerGen investigators contribute to breakthrough Treg discovery

A recent discovery from the Research Institute of the McGill University Health Centre (RI-MUHC) suggests autoimmune and chronic inflammatory diseases may be linked to mutations in a critical gene. The discovery also sheds new light on the function of Regulatory

Quality of mothers’ care in early life linked to atopic dermatitis in infants

Until recently, little was known about the association between the mother-child relationship early in life and the development of atopic dermatitis (AD), a childhood skin disease that is often the first step in the “atopic march” toward allergic rhinitis and

What saliva says about stress

A salivary gland protein is an effective biological marker of human stress, according to new research led by Dr. Dean Befus, an AllerGen Research Leader and a professor of Pulmonary Medicine at the University of Alberta. The research, published in

New CHILD Study paper on timing of food introduction & development of food sensitization

Delaying the introduction of potentially allergenic foods until after a baby’s first year may increase the likelihood of a food allergy later on, according to new findings from the Canadian Healthy Infant Longitudinal Development (CHILD) Study. The research, published in